Article

Switching of OAS1 splicing isoforms mitigates SARS-CoV-2 infection

2021-08-23

Abstract excerpt

<h4>Background</h4> The rapidly accumulating disease susceptibility information collected from coronavirus disease (COVID-19) patient genomes must be urgently utilized to develop therapeutic interventions for SARS-CoV-2 infection. Chromosome 12q24.13, which encodes the 2’-5’-oligoadenylate synthetase (OAS) family of proteins that sense viral genomic RNAs and trigger an antiviral response, is identified as one of...

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Literature Corpus work: 5852df6b-3d58-5dc5-af7c-8bb823be85fa
DOI: 10.1101/2021.08.23.457314

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