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Low-dose inorganic arsenic exposure reprograms macrophages differentiation and function toward tumor-promoting phenotypes.

Environmental research - 15 Aug 2026

Illingworth Emily J, Sanchez Sylvia S, Rychlik Kristal A, Kleensang Andre, Laird Jason, Lopez-Cecetaite Gabriel A, Rodriguez Steube M Carolina, Mathur Aakriti, Sadhukhan Pritam, Medina-Cleghorn Daniel A, Nomura Daniel, Smith Martyn T, Hoque Mohammad O, Sillé Fenna C M

Abstract excerpt

Inorganic arsenic (iAs) is a known carcinogen and immunotoxicant that contaminates groundwater used for drinking, food production, and irrigation, exposing an estimated 200 million people worldwide to levels above the World Health Organization safe drinking water limit of 10 μg/L. Classified as a known carcinogen classified by the International Agency for Research on Cancer (IARC), iAs alsond causes increasesd...

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PMID: 42105843
DOI: 10.1016/j.envres.2026.124699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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