Article
Evaluating Macrophages in Immunotoxicity Testing.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Franko Jennifer, McCall Jamie L, Barnett John B
Abstract excerpt
Macrophages are a heterogeneous group of cells that have a multitude of functions depending on their differentiation state. While classically known for their phagocytic and antigen presentation abilities, it is now evident that these cells fulfill homeostatic functions beyond the elimination of invading pathogens. In addition, macrophages have also been implicated in the downregulation of inflammatory responses...
Topics
- Animals
- Antigen Presentation
- Apoptosis
- Autophagy
- Biological Assay
- Humans
- Macrophage Activation
- Macrophages
- Mice
- Models, Biological
- Phagocytosis
- Phenotype