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Article

Early-life Exposure to Arsenic Primes the Offspring to Increased Asthma Risk: Transcriptome and Epigenome Analysis

2025-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Inorganic arsenic (iAs) in drinking water is a global health concern. This study tests whether maternal exposure to iAs in drinking water at the WHO provisional level (10µg/L) increases offspring asthma risk via epigenetic reprogramming. F1 mice prenatally exposed to iAs were analyzed at 5 months for blood transcriptome and methylome changes and challenged with house allergens before lung functi...

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Literature Corpus work
56a08d6a-16af-5e05-93f6-c0630491ef14
DOI
10.1101/2025.08.01.668223
Open publication

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