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Article

Human macrophages constitute targets for immunotoxic inorganic arsenic.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2006

Lemarie Anthony, Morzadec Claudie, Bourdonnay Emilie, Fardel Olivier, Vernhet Laurent

Abstract excerpt

Chronic exposure to inorganic arsenic, a widely distributed environmental contaminant, can lead to toxic effects, including immunosuppression. Owing to the established roles of human macrophages in immune defense, we determined, in the present study, whether inorganic arsenic can affect these major immune cells. Our results demonstrate that noncytotoxic concentrations of arsenic trioxide (As2O3), an inorganic...

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PMID: 16920938
DOI: 10.4049/jimmunol.177.5.3019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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