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Article

METTL5 enhances the mRNA stability of TPRKB through m6A modification to facilitate the aggressive phenotypes of hepatocellular carcinoma cell.

Experimental cell research - 1 Sept 2024

Luo Ming, Luo Xiong, Sun Jichun, Ao Xiang, Han Haoyan, Yang Xin

Abstract excerpt

N6-methyladenosine (m6A) modification plays an important role in RNA molecular functions, therefore affecting the initiation and development of hepatocellular carcinoma (HCC). Herein, multiple datasets were applied to conduct a comprehensive analysis of DEGs within HCC and the analysis revealed significant dysregulation of numerous genes. Functional and signaling pathway enrichment analyses were performed....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39182664
DOI: 10.1016/j.yexcr.2024.114219

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