Article

Motor and Nonmotor Features of p.A53T Alpha-Synuclein PD vs idiopathic PD: Longitudinal Data from the PPMI Study.

2024-08-23

Abstract excerpt

<h4>Background: </h4> and Objectives: The phenotype of p.A53T-SNCA Parkinson's Disease (PD) mutation carriers appears more severe than that of iPD patients, however comprehensive comparative prospective studies are lacking. Here we conducted a longitudinal study to investigate, using multiple parameters, the progression of motor and nonmotor features of p.A53T-PD compared to iPD. <h4>Methods:</h4> Longitudinal 3-y...

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Literature Corpus work: 578b7561-7c5e-503c-a05f-9cffb821c5fa
DOI: 10.1101/2024.08.23.24312442

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