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Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samples

2021-05-18

Abstract excerpt

<h4>Background</h4> DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between perinatal DNA methylation marks and pregnancy-related variables, such as maternal age and gestational weight gain, have been earlier studied with methylation microarrays, which typically cover less than 2 % of human CpG sites. To detect s...

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Literature Corpus work
57573a2b-ca2b-5b62-9824-b6852cb25bb8
DOI
10.1101/2021.05.18.444359
Open publication

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Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samplesDOI 10.1101/2021.05.18.444359
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