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Transcriptional Drug Repositioning Improves Development Of Somatic Cell Nuclear Transfer Embryos Via Inhibition Of CDK4/6 And Cyclin D1 During First Cleavage of Bovine Pseudo-Zygotes

2021-04-28

Abstract excerpt

Since the birth of the first cloned sheep, ‘Dolly’, Somatic Cell Nuclear Transfer (SCNT) has become a powerful method in the fields of agricultural and biomedical research. However, due to the accumulation of errors during nuclear reprogramming, the efficiency of this technique remained low. In this study, we applied a transcriptional drug repositioning approach for selecting small molecules to improve SCNT effici...

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Literature Corpus work: 5756409d-69c8-59f0-833e-1de76719fa4a
DOI: 10.21203/rs.3.rs-450025/v1

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Transcriptional Drug Repositioning Improves Development Of Somatic Cell Nuclear Transfer Embryos Via Inhibition Of CDK4/6 And Cyclin D1 During First Cleavage of Bovine Pseudo-ZygotesDOI 10.21203/rs.3.rs-450025/v1Read

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