Article

Rare coding variants in axonemal dynein heavy chain genes are associated with adolescent idiopathic scoliosis

2020-12-28

Abstract excerpt

<title>Abstract</title> <p>Adolescent idiopathic scoliosis (AIS) is the most common pediatric musculoskeletal disorder worldwide, characterized by atypical spine curvatures in otherwise healthy children. Human genetic studies have identified candidate genes associated with AIS, however, only a few of these genes have been shown to recapitulate adult-viable scoliosis in animal models. To further define susceptibil...

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Literature Corpus work: 8199f1b5-0efe-5c8e-89b6-d5e414a2b133
DOI: 10.21203/rs.3.rs-121210/v1

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