Article

Real-time in vivo quantification of human skeletal muscle metabolism during exercise using hyperpolarised [1-¹³C]pyruvate reveals training-dependent metabolic adaptation

2026-05-04

Abstract excerpt

<title>Abstract</title> <p>Skeletal muscle is defined by rapid and dynamic fluctuations in ATP demand during exercise, limiting the physiological relevance of resting-state measurements. Here, we show that hyperpolarised ¹³C magnetic resonance spectroscopy (¹³C-MRS), integrated with ³¹P-MRS, enables non-invasive, real-time resolution of mitochondrial and non-mitochondrial energy metabolism in human skeletal muscl...

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Literature Corpus work: 404d1b4f-af4b-565e-8076-c3cc983115e4
DOI: 10.21203/rs.3.rs-9474853/v1

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Real-time in vivo quantification of human skeletal muscle metabolism during exercise using hyperpolarised [1-¹³C]pyruvate reveals training-dependent metabolic adaptationDOI 10.21203/rs.3.rs-9474853/v1Read

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