Article

Mononuclear phagocyte activation and its role in HIV-1 pathogenesis

2009-01-01

Abstract excerpt

Three decades into the HIV-1 pandemic, it is increasingly apparent that generalized immune activation is a key pathogenic determinant of AIDS. Studies of immune activation, in the setting of HIV-1, have focused primarily on the adaptive immune response despite the role of monocytes and macrophages as key regulators of inflammatory responses. In this thesis, I focused on the relationships between mononuclear phagoc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 571a5210-d0c2-5390-8826-e23365894ef2
DOI: 10.21954/ou.ro.0000d574

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mononuclear phagocyte activation and its role in HIV-1 pathogenesisDOI 10.21954/ou.ro.0000d574Read

Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a pro-inflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral productionSemantic proximity Read

Macrophage polarization at the crossroad between HIV-1 infection and cancer development.Semantic proximity Read

Myeloid Cell Interaction with HIV: A Complex RelationshipSemantic proximity Read

Macrophage polarization: convergence point targeted by Mycobacterium tuberculosis and HIVSemantic proximity Read

Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirsSemantic proximity Read

Monocytes and Macrophages as Viral Targets and ReservoirsSemantic proximity Read

Immune activation in the course of HIV-1 infection: Causes, phenotypes and persistence under therapy.Semantic proximity Read

Phenotypic Diversity and Emerging New Tools to Study Macrophage Activation in Bacterial Infectious DiseasesSemantic proximity Read

Macrophage polarization in infectious diseases: PAMP, viru-lence factors, immune signaling and receptorsSemantic proximity Read

Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivationSemantic proximity Read

Macrophages and their relevance in Human Immunodeficiency Virus Type I infectionSemantic proximity Read

Persistent Inflammation and Non-AIDS Comorbidities During ART: Coming of the Age of MonocytesSemantic proximity Read