Article

Exploring the role of CAG repeats in HTT, ATXN1 and ATXN2 genes in the genetic architecture of mental disorders: schizophrenia and bipolar disorder

2026-04-28

Abstract excerpt

<title>Abstract</title> <p> Schizophrenia (SCZ) and bipolar disorder (BD) are complex psychiatric disorders with partially overlapping genetic architectures and shared features with neurodegenerative diseases. Short tandem repeats (STRs), particularly CAG expansions in <italic>HTT</italic> , <italic>ATXN1</italic> and <italic>ATXN2</italic> , are established causes of neurodegenerative disorders, yet their...

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Literature Corpus work: 57097de6-3b99-5b74-af25-91cead2adb60
DOI: 10.21203/rs.3.rs-9428416/v1

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