Article

Human cellular genetics of innate immunity

2020-01-01

Abstract excerpt

The type I interferon response is a key part of the innate immune system, responding to infection and inducing an antiviral intracellular state. While there is known to be variability in this signalling pathway between individuals, alongside cell-to-cell heterogeneity in a genetically identical cell population, the basis of this variation is not fully understood. In this PhD, I established large-scale single-cell...

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Literature Corpus work: 5706b2e5-6e94-5d0b-a62b-0bd7af0a7946
DOI: 10.17863/cam.46537

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