Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-transcriptome sequencing–based concomitant detection of viral and human genetic determinants of cutaneous lesions

22 Mar 2022

Abstract excerpt

Severe viral infections of the skin can occur in patients with inborn errors of immunity (IEI). We report an all-in-one whole-transcriptome sequencing-based method by RNA-Seq on a single skin biopsy for concomitantly identifying the cutaneous virome and the underlying IEI. Skin biopsies were obtained from healthy and lesional skin from patients with cutaneous infections suspected to be of viral origin. RNA-Seq...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunodeficiency and Autoimmune Disorders
Share to Parvovirus B19 Infection Studies
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35316210
DOI: 10.1172/jci.insight.156021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-transcriptome sequencing–based concomitant detection of viral and human genetic determinants of cutaneous lesionsPMID 35316210Read ↗

Whole transcriptome–based skin virome profiling in typical epidermodysplasia verruciformis reveals α-, β-, and γ-HPV infectionsSemantic proximity Read ↗

Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden.Semantic proximity Read ↗

Genetic diagnosis of inborn errors of immunity using clinical exome sequencingSemantic proximity Read ↗

Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders.Semantic proximity Read ↗

NGS data analysis for molecular diagnosis of Inborn Errors of Immunity.Semantic proximity Read ↗

The genetic architecture of human infectious diseases and pathogen-induced cellular phenotypesSemantic proximity Read ↗

Clinical Utility of Whole Exome Sequencing and Targeted Panels for the Identification of Inborn Errors of Immunity in a Resource-Constrained SettingSemantic proximity Read ↗

GRID – Genomics of Rare Immune Disorders: a highly sensitive and specific diagnostic gene panel for patients with primary immunodeficienciesSemantic proximity Read ↗

Genetic Evaluation of the Patients with Clinically Diagnosed Inborn Errors of Immunity by Whole Exome Sequencing: Results from a Specialized Research Center for Immunodeficiency in Türkiye.Semantic proximity Read ↗

Whole Genome Sequencing in 25 Families with Suspected Inborn Errors of Immunity: Diagnostic Yield and Clinical Relevance of Genome-wide Analysis.Semantic proximity Read ↗

Genomic and clinical characterization of adult CVID patients: results from a single-centre turkish cohort.Semantic proximity Read ↗

Clinical and molecular profile of 20 patients with DOCK8 deficiency-a single-center experience from Southern India.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.