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Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case-Control Study

2025-10-17

Abstract excerpt

<h4>Objectives: </h4> Breast cancer (BC) is the most common malignancy among Bangladeshi women. Mouse Double Minute 4 (MDM4) gene polymorphisms have been implicated in BC susceptibility, but data from South Asian populations remain limited. MDM4 is a key negative regulator of the p53 tumor suppressor pathway, and its genetic variants may influence cancer risk through altered p53 signaling. <h4>Methods:</h4> This c...

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Literature Corpus work: 56a9bd45-e0aa-5512-8d7d-d1061009f1c9
DOI: 10.20944/preprints202510.1202.v1

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