Article
Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case-Control Study.
Journal of clinical laboratory analysis - 1 May 2026
Islam J M Aousiful, Ahamed Sharif, Islam Shafiqul, Hossain M Mahboob, Hossain Md Sadbean, Mostaid Md Shaki, Islam Md Rabiul, Haque Md Aminul
Abstract excerpt
BACKGROUND: Breast cancer (BC) is the most common malignancy among Bangladeshi women. MDM4 gene polymorphisms have been implicated in BC susceptibility, but data from South Asian populations remain limited. METHODS: This case-control study included 112 BC patients from a cancer hospital, Dhaka, Bangladesh, and 124 age- and sex-matched healthy controls (HC) from the surrounding areas. Genotyping of MDM4 rs1380576...
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