Article

A somatic afterhyperpolarization is driven by ion channel nodes expressed across a polygonal spectrin cytoskeleton

2024-08-09

Abstract excerpt

<h4>Summary</h4> A spectrin-actin cytoskeleton defines the structure of axons and expression of ion channels that support spike propagation, but it is not known how calcium and potassium channels are organized at the soma to control spike output patterns. The hippocampal pyramidal cell slow afterhyperpolarization (sAHP) is generated by a CaRyK protein complex of Cav1.3 calcium, RyR2, and IK potassium channels ref...

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Literature Corpus work: 56973c8c-a128-5831-95b9-c1bf32486ee4
DOI: 10.1101/2024.08.08.607230

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