Article

DNA crosslink repair safeguards genomic stability during pre-meiotic germ cell development

2020-01-01

Abstract excerpt

Germ cells are single-handedly responsible for the transmission of genetic and epigenetic information (the instructions to make new life) from one generation to the next. It is therefore, of paramount importance that germ cells maintain the stability of their genome. Failure to do so can result in the transmission of de novo mutations to offspring. Germline de novo mutations are the basis of genetic disease and th...

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Literature Corpus work: 5677e861-6912-5bd4-802c-49ffca579598
DOI: 10.17863/cam.66360

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