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Article

Elastin Peptides: A Disease Vector in the Pathogenesis of Pulmonary Emphysema

2025-01-29

Abstract excerpt

The degradation of elastic fibers is a fundamental characteristic of pulmonary emphysema, resulting in the release of proinflammatory elastin peptides. The findings discussed in this paper support the hypothesis that these peptides act as carriers of disease, interacting with elastin receptor complexes that promote inflammation, elastic fiber damage, and airspace enlargement. Studies from our laboratory show that...

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Literature Corpus work
565df361-ba5b-5616-8f0d-0553221bfef2
DOI
10.20944/preprints202501.2174.v1
Open publication

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