Article

Elastin-derived peptides suppress CCL20 expression and block ILC2 recruitment during lung inflammation

2026-06-23

Abstract excerpt

Elastin degradation during chronic lung inflammation generates elastin peptides (EPs) with immunomodulatory properties. Because elastin is abundant in the lung, its breakdown in diseases such as chronic obstructive pulmonary disease (COPD) and asthma produces high EPs levels that may influence local immune responses. Here, we investigated the impact of EPs on group 2 innate lymphoid cells (ILC2) using mouse models...

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Literature Corpus work: 5e041bad-3ccd-511a-a073-5a7e4ad624dd
DOI: 10.64898/2026.06.18.733133

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