Article
The pathogenesis of pulmonary fibrosis: a moving target.
The European respiratory journal - 1 May 2013
Wuyts Wim A, Agostini Carlo, Antoniou Katerina M, Bouros Demosthenes, Chambers Rachel C, Cottin Vincent, Egan Jim J, Lambrecht Bart N, Lories Rik, Parfrey Helen, Prasse Antje, Robalo-Cordeiro Carlos, Verbeken Eric, Verschakelen Johny A, Wells Athol U, Verleden Geert M
Abstract excerpt
Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is characterised by excessive matrix formation leading to destruction of the normal lung architecture and finally death. Despite an exponential increase in our understanding of potentially important mediators and mechanisms, the delineation of primary pathways has proven to be elusive. In this review susceptibility and injurious...
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