Article

Mapping SOX9 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells

2021-11-29

Abstract excerpt

The master transcription factor SOX9 is a key player during chondrocyte differentiation, cartilage development, homeostasis and disease. Modulation of SOX9 and its target gene expression is essential during chondrogenic, osteogenic and adipogenic differentiation of human mesenchymal stem cells (hMSCs). However, lack of sufficient knowledge about the signaling interplay during differentiation remains one of the mai...

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Literature Corpus work: 55cb8360-6d04-5062-aa2f-9fc48c1d238b
DOI: 10.1101/2021.11.29.470107

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