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Article

High-resolution myogenic lineage mapping by single-cell mass cytometry.

Nature cell biology - 1 May 2017

Porpiglia Ermelinda, Samusik Nikolay, Ho Andrew Tri Van, Cosgrove Benjamin D, Mai Thach, Davis Kara L, Jager Astraea, Nolan Garry P, Bendall Sean C, Fantl Wendy J, Blau Helen M

Abstract excerpt

Muscle regeneration is a dynamic process during which cell state and identity change over time. A major roadblock has been a lack of tools to resolve a myogenic progression in vivo. Here we capitalize on a transformative technology, single-cell mass cytometry (CyTOF), to identify in vivo skeletal muscle stem cell and previously unrecognized progenitor populations that precede differentiation. We discovered two...

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Identifiers

PMID: 28414312
DOI: 10.1038/ncb3507
PMCID: PMC5728993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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