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Article

The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.

Arthritis and rheumatism - 1 Nov 2004

Ikeda Toshiyuki, Kamekura Satoru, Mabuchi Akihiko, Kou Ikuyo, Seki Shoji, Takato Tsuyoshi, Nakamura Kozo, Kawaguchi Hiroshi, Ikegawa Shiro, Chung Ung-il

Abstract excerpt

OBJECTIVE: To regenerate permanent cartilage, it is crucial to know not only the necessary conditions for chondrogenesis, but also the sufficient conditions. The objective of this study was to determine the signal sufficient for chondrogenesis. METHODS: Embryonic stem cells that had been engineered to fluoresce upon chondrocyte differentiation were treated with combinations of factors necessary for...

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Share to Cartilage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15529345
DOI: 10.1002/art.20611

Genes

SOX5
SOX6
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

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The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.PMID 15529345Read ↗

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