Article

Non-invasive ²³Na MRI Identifies Functionally Distinct Cyst Phenotypes in Autosomal Dominant Polycystic Kidney Disease

2026-08-02

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cysts from different nephron segments, yet their origin remains inaccessible to in vivo imaging. Building on ex vivo studies that cyst sodium concentration ([Na⁺]) may reflect tubular origin, we developed a non-invasive 23 Na magnetic resonance imaging (MRI) approach at 7 Tesla to phenotype ADPKD cysts in vivo based on cyst sodium. In nephre...

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Literature Corpus work: 55b55286-b6d5-5767-9097-b9dae5bbbb20
DOI: 10.64898/2026.07.30.26359242

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