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Article

Magnetic resonance T2 mapping and diffusion-weighted imaging for early detection of cystogenesis and response to therapy in a mouse model of polycystic kidney disease.

Kidney international - 1 Dec 2017

Franke Mareike, Baeßler Bettina, Vechtel Jan, Dafinger Claudia, Höhne Martin, Borgal Lori, Göbel Heike, Koerber Friederike, Maintz David, Benzing Thomas, Schermer Bernhard, Persigehl Thorsten

Abstract excerpt

Polycystic kidney disease (PKD) is among the leading causes of end-stage renal disease. Increasing evidence exists that molecular therapeutic strategies targeted to cyst formation and growth might be more efficacious in early disease stages, highlighting the growing need for sensitive biomarkers. Here we apply quantitative magnetic resonance imaging techniques of T2 mapping and diffusion-weighted imaging in the...

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PMID: 28754558
DOI: 10.1016/j.kint.2017.05.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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