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Article

Choice of lipid supplementation for <i>in vitro</i> erythroid cell culture impacts reticulocyte yield and characteristics

2025-07-12

Abstract excerpt

Lipids, particularly cholesterol, are critical components of red blood cell (RBC) membranes, influencing protein function, cell stability, and deformability. Reticulocytes (young RBC) derived from in vitro erythroid cultures have been reported to possess less cholesterol than their native counterparts, compromising their functional integrity and lifespan. However, variability in starting materials and culture pro...

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Literature Corpus work
55b1180c-b6dd-5768-bc31-e6fb9cc689d7
DOI
10.1101/2025.07.11.664344
Open publication

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Choice of lipid supplementation for <i>in vitro</i> erythroid cell culture impacts reticulocyte yield and characteristicsDOI 10.1101/2025.07.11.664344
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