Article
Choice of lipid supplementation for <i>in vitro</i> erythroid cell culture impacts reticulocyte yield and characteristics
2025-07-12
Abstract excerpt
Lipids, particularly cholesterol, are critical components of red blood cell (RBC) membranes, influencing protein function, cell stability, and deformability. Reticulocytes (young RBC) derived from in vitro erythroid cultures have been reported to possess less cholesterol than their native counterparts, compromising their functional integrity and lifespan. However, variability in starting materials and culture pro...
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Identifiers and source
- Literature Corpus work
- 55b1180c-b6dd-5768-bc31-e6fb9cc689d7
- DOI
- 10.1101/2025.07.11.664344
