Back to search

Article

Accessory-cell-free differentiation of hematopoietic stem and progenitor cells into mature red blood cells

2022-09-16

Abstract excerpt

<h4>ABSTRACT</h4> The culture and ex vivo engineering of red blood cells (RBCs) can help characterize genetic variants, model diseases, and may eventually spur the development of applications in transfusion medicine. In the last decade, improvements to the in vitro production of RBCs have enabled efficient erythroid progenitor proliferation and high enucleation levels from several sources of hematopoietic stem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a564fa17-7260-5477-8f6b-b363c6b15fa3
DOI
10.1101/2022.09.14.507311
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Accessory-cell-free differentiation of hematopoietic stem and progenitor cells into mature red blood cellsDOI 10.1101/2022.09.14.507311
Concise Review: Stem Cell‐Derived Erythrocytes as Upcoming Players in Blood TransfusionSemantic proximity
Erythroid cells in vitro: from developmental biology to blood transfusion productsSemantic proximity
An In Vitro Model of Human Red Blood Cell Production From Hematopoietic Progenitor CellsSemantic proximity
Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivoSemantic proximity
Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeuticsSemantic proximity
Scalable Production of Human Erythrocytes from Induced Pluripotent Stem CellsSemantic proximity
Decoding human <i>in vitro</i> terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cellsSemantic proximity
Primitive and definitive erythropoiesis in mammalsSemantic proximity
Ex-vivo generation of human red cells for transfusionSemantic proximity
Ex vivo generation of fully mature human red blood cells from hematopoietic stem cellsSemantic proximity
Biologic properties and enucleation of red blood cells from human embryonic stem cellsSemantic proximity
Advances in understanding erythropoiesis: evolving perspectivesSemantic proximity
Select a neighboring publication to make it the new centre.