Article

Generation of broad-spectrum vaccine platforms against tick-borne flaviviruses using ancestral sequence reconstruction

2025-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Tick-Borne Flaviviruses (TBFs) pose a significant global health threat, but few vaccines exist against these viral pathogens. Currently approved vaccines against TBFs are only protective against specific virus species, leaving the population at risk for infection by many existing and emerging TBFs. The development of vaccines that provide broad protection against a range of related TBFs has the...

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Literature Corpus work: 5548a9ea-e287-5fef-9c42-3c62f3fb70e7
DOI: 10.1101/2025.10.31.685878

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