Article

Cold-mediated regulation of systemic retinol transport controls adipose tissue browning

2020-02-07

Abstract excerpt

<h4>ABSTRACT</h4> Browning of white fat reduces obesity in many preclinical models. Vitamin A metabolites (retinoids) have been linked to thermogenic programming of adipose tissue (AT), however the physiologic importance of systemic retinoid metabolism for AT browning is unknown. Here we show that cold stimulation in mice and humans increases circulating retinol and its plasma transporter, retinol binding protein...

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Literature Corpus work: 552fcc1b-113e-5e33-8171-446f64216232
DOI: 10.1101/2020.02.07.938688

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