Article

Glucocorticoid Programming of Erythrocyte Hypoxic Memory Enables Rapid High-Altitude Acclimatization

2026-05-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Rapid ascent to high altitude causes acute mountain sickness (AMS) and life-threatening pulmonary/cerebral edema, yet no prophylaxis enables immediate acclimatization. Intermittent hypoxia training (IHT) establishes a “hypoxic memory” that accelerates adaptation, to high altitude, but its cellular and molecular basis remains undefined, precluding effective pharmacological st...

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Literature Corpus work: 552edf3a-232a-58a8-b839-43d0631c9133
DOI: 10.64898/2026.05.26.728051

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