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Article

The Xenobiotic Extrusion Mechanism of the MATE Transporter NorM_PS from Pseudomonas stutzeri.

Journal of molecular biology - 27 Apr 2018

Eisinger Martin Lorenz, Nie Laiyin, Dörrbaum Aline Ricarda, Langer Julian David, Michel Hartmut

Abstract excerpt

Multidrug resistance (MDR) in bacterial pathogens has become a severe threat to public health. Membrane transporters of the multidrug and toxic compound extrusion (MATE) family contribute critically to MDR, making them promising drug targets. Despite recent advances, structures in different conformations and the mechanistic details of their antiport cycle are still elusive. Here we studied NorM_PS, a...

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PMID: 29555555
DOI: 10.1016/j.jmb.2018.03.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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