Article

Discovery of a unique Ni2+-dependent heterohexameric metformin hydrolase

2024-01-31

Abstract excerpt

<title>Abstract</title> <p>The biguanide drug metformin is prescribed worldwide as a first-line blood glucose-lowering medication for type 2 diabetes, leading to its presence in the environment around the world. Despite mounting evidence indicating that metabolic interactions of metformin with environmental or intestinal microbes affect ecological and human health, little is known about the fate of metformin by m...

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Literature Corpus work: 299b18e8-8921-587b-9ca7-6c23636b33f8
DOI: 10.21203/rs.3.rs-3656883/v1

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