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Article

Cancer-associated HIF-2α impacts trunk neural crest stemness

2020-01-23

Abstract excerpt

The neural crest is a stem cell population that gives rise to sympathetic ganglia, the cell type of origin of neuroblastoma. Hypoxia Inducible Factor (HIF)-2α is associated with high risk neuroblastoma, however, little is known about its role in normal neural crest development. To address this important question, here we show that HIF-2α is expressed in trunk neural crest cells of human, murine and avian embryos....

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Literature Corpus work
547c40d4-ec4a-5e11-9421-c8060d5ba004
DOI
10.1101/2020.01.22.915199
Open publication

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Cancer-associated HIF-2α impacts trunk neural crest stemnessDOI 10.1101/2020.01.22.915199
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