Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes.

Abstract excerpt

Although genome-scale analyses have provided insights into the connection between genetic variability and complex human phenotypes, much trait variation is still not fully understood. Genetic variation within repetitive elements, such as the multi-copy, multi-locus ribosomal DNA (rDNA), has emerged as a potential contributor to trait variation. Whereas rDNA was long believed to be largely uniform within a...

Topics

• Humans
• Phenotype
• DNA, Ribosomal
• Genetic Variation
• DNA Copy Number Variations