Article

Novel, broad and potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

2023-11-14

Abstract excerpt

<title>Abstract</title> <p>The continuous emergence of SARS-CoV-2 variants of concern with mutated spike receptor binding domains has rendered many therapeutic mAbs ineffective. To date, there are no clinically authorized therapeutic antibodies effective against the predominant circulating sub-lineages BQ and XBB. Here, we report the isolation of broad and potent neutralizing HuMabs from a Danish healthcare worke...

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Literature Corpus work: 542a53d3-e0e0-5b80-a5e1-918b0ecbd49c
DOI: 10.21203/rs.3.rs-3062716/v1

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