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Anti-Cancer Outcome of Glucocorticoid Receptor Transrepression by Synephrine Derivatives

2025-10-24

Abstract excerpt

<h4>Background: </h4> /Objectives: Glucocorticoids (GCs) present effective anti-cancer drugs for the treatment of hematological malignancies but their clinical use is limited due to their multiple adverse effects. Selective glucocorticoid receptor agonists/modulators (SEGRAMs) modify glucocorticoid receptor (GR) function shifting it towards therapeutically important transrepression and, therefore, could be safer a...

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Literature Corpus work
54003f0c-0714-520d-a5e6-fd9e8fd13371
DOI
10.20944/preprints202510.1879.v1
Open publication

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Anti-Cancer Outcome of Glucocorticoid Receptor Transrepression by Synephrine DerivativesDOI 10.20944/preprints202510.1879.v1
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