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Article

Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them?

24 Sept 2020

Abstract excerpt

Exogenous glucocorticoids are widely used in the clinic for the treatment of inflammatory disorders and hematological cancers. Unfortunately, their use is associated with debilitating side effects, including hyperglycemia, osteoporosis, mood swings, and weight gain. Despite the continued efforts of pharma as well as academia, the search for so-called selective glucocorticoid receptor modulators (SEGRMs),...

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PMID: 33071974
DOI: 10.3389/fendo.2020.559673

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