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Duality of glucocorticoid action in cancer: tumor-suppressor or oncogene?

14 Apr 2021

Abstract excerpt

Glucocorticoid receptor (GR) is a key homeostatic regulator involved in governing immune response, neuro-integration, metabolism and lung function. In conjunction with its pivotal role in human biology, GR action is critically linked to the pathology of various disease types, including cancer. While pharmacological activation of GR has been used for the treatment of various liquid cancers, its role in solid...

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PMID: 33852423
DOI: 10.1530/erc-20-0489

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