Article

Spatiotemporal map of the developing human reproductive tract at single-cell resolution

2024-10-31

Abstract excerpt

The human reproductive tract plays an essential role in species perpetuation. Its development involves complex processes of sex specification, tissue patterning and morphogenesis, which, if disrupted, can cause lifelong health issues, including infertility. Here, we generated an extensive single-cell and spatial multi-omic atlas of the human reproductive tract during prenatal development, which allowed us to answe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ead2d6f8-e849-565c-adb1-eec89a381819
DOI: 10.1101/2024.10.30.621114

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spatiotemporal map of the developing human reproductive tract at single-cell resolutionDOI 10.1101/2024.10.30.621114Read

Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomicsSemantic proximity Read

Genetic and genomic insights into male reproductive tract development.Semantic proximity Read

Characterization of the human fetal rete region by single cell transcriptional analysis of gonads and mesonephros/epididymisSemantic proximity Read

The role of HOX genes in the development and function of the female reproductive tract.Semantic proximity Read

A tale of two tracts: history, current advances, and future directions of research on sexual differentiation of reproductive tracts†Semantic proximity Read

Single-cell roadmap of human gonadal developmentSemantic proximity Read

The Genomic Architecture of Bladder Exstrophy Epispadias Complex.Semantic proximity Read

Development of the Mammalian Female Reproductive TractSemantic proximity Read

An extra-genital cell population contributes to urethra closure during mouse penis developmentSemantic proximity Read

Sex Determination and Gonadal Development in MammalsSemantic proximity Read

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasetsSemantic proximity Read

Mechanistic Drivers of Müllerian Duct Development and Differentiation Into the OviductSemantic proximity Read