Article

Tbxt alleviates senescence and apoptosis of nucleus pulposus cells through Atg7 mediated autophagy activation during intervertebral disc degeneration

2023-10-28

Abstract excerpt

<title>Abstract</title> <p>Intervertebral disc degeneration (IDD) is a significant cause of low back pain, characterized by excessive senescence and apoptosis of nucleus pulposus cells (NPCs). However, the precise mechanisms behind this senescence and apoptosis remains unclear. This study aimed to investigate the role of Tbxt in IDD both <italic>in vitro</italic> and <italic>in vivo</italic>, using a hydrogen per...

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Literature Corpus work: 53bccf26-8266-57e4-9f8b-7a4b46accf79
DOI: 10.21203/rs.3.rs-3481551/v1

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