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Aging, cell senescence, the pathogenesis and targeted therapies of intervertebral disc degeneration

5 May 2023

Abstract excerpt

Intervertebral disc degeneration (IVDD) refers to the aging and degenerative diseases of intervertebral disc components such as nucleus pulposus, annulus fibrosus, and cartilage endplate, and is the main cause of chronic low back pain. Over the past few years, many researchers around the world concerned that the degeneration of nucleus pulposus (NP) cells plays the main role in IVDD. The degeneration of NP cells...

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PMID: 37214476
DOI: 10.3389/fphar.2023.1172920

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