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Article

Targeting Autophagy for Developing New Therapeutic Strategy in Intervertebral Disc Degeneration

14 Aug 2022

Abstract excerpt

Intervertebral disc degeneration (IVDD) is a prevalent cause of low back pain. IVDD is characterized by abnormal expression of extracellular matrix components such as collagen and aggrecan. In addition, it results in dysfunctional growth, senescence, and death of intervertebral cells. The biological pathways involved in the development and progression of IVDD are not fully understood. Therefore, a better...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36009290
DOI: 10.3390/antiox11081571

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