Article

Temporal multi-omic analysis of COVID-19 in end-stage kidney disease

2024-06-24

Abstract excerpt

<h4>Summary</h4> Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. We performed longitudinal single cell multi-omic immune profiling of ESKD patients with COVID- 19, sampled during two waves of the pandemic. Uniquely, for a subset of patients, we obtained samples before and during acute infection, allowing intra-individual comparison. Using single- cell transcriptome, surface prote...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8f3d986f-c7dd-55bd-94a0-904bfabe1077
DOI: 10.1101/2024.06.20.24309228

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Temporal multi-omic analysis of COVID-19 in end-stage kidney diseaseDOI 10.1101/2024.06.20.24309228Read

Single-cell multi-omics analysis of the immune response in COVID-19Semantic proximity Read

3D genomic capture of regulatory immuno-genetic profiles in COVID-19 patients for prognosis of severe COVID disease outcomeSemantic proximity Read

Multi-omics identify LRRC15 as a COVID-19 severity predictor and persistent pro-thrombotic signals in convalescenceSemantic proximity Read

The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centresSemantic proximity Read

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection TrajectoriesSemantic proximity Read

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection TrajectoriesSemantic proximity Read

Single-Cell RNA Sequencing of Urinary Cells Reveals Distinct Cellular Diversity in COVID-19–Associated AKISemantic proximity Read

Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populationsSemantic proximity Read

The COVIDome Explorer Researcher PortalSemantic proximity Read

Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participantsSemantic proximity Read

Unveiling the Immune Landscape of COVID-19 and prolonged Long-COVID through Single-Cell RNA SequencingSemantic proximity Read

Immune Cell Profiling of COVID-19 Patients in the Recovery Stage by Single-Cell SequencingSemantic proximity Read