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Screening the Medicines for Malaria Pandemic Response Box chemical library on <i>Caenorhabditis elegans</i> identifies re-profiled candidate anthelmintic drug leads

2022-08-13

Abstract excerpt

The 3 major classes of soil transmitted helminths (whipworm, hookworm and Ascaris) affect 1.5 billion people worldwide mostly in poor countries, where they have adverse effects on child development, nutrition, and the work capacity of adults. Although there are drugs effective on Ascaris, notably the benzimidazoles, those same drugs show poor efficacy particularly against whipworm ( Trichuris trichiura ) and to a...

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Literature Corpus work
53a0fef2-5182-5783-9d76-460b10db02e9
DOI
10.1101/2022.08.10.503491
Open publication

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Screening the Medicines for Malaria Pandemic Response Box chemical library on <i>Caenorhabditis elegans</i> identifies re-profiled candidate anthelmintic drug leadsDOI 10.1101/2022.08.10.503491
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