Article
Anthelmintic drug discovery: into the future.
The Journal of parasitology - 1 Apr 2015
Geary Timothy G, Sakanari Judy A, Caffrey Conor R
Abstract excerpt
The last half-century has provided all of the (few) drugs currently used to treat human helminthiases. Concern regarding the long-term utility of these drugs, given how readily resistance evolves in the veterinary-agricultural sector, spurs the discovery of new chemical entities. We review the approaches and technologies in use to identify anthelmintics and discuss a number of drug discovery paradigms that may...
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