Article
Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility.
Proceedings of the National Academy of Sciences of the United States of America - 30 Mar 2010
Hu Yan, Platzer Edward G, Bellier Audrey, Aroian Raffi V
Abstract excerpt
The soil-transmitted helminths or nematodes (hookworms, whipworms, and Ascaris) are roundworms that infect more than 1 billion of the poorest peoples and are leading causes of morbidity worldwide. Few anthelmintics are available for treatment, and only one is commonly used in mass drug administrations. New anthelmintics are urgently needed, and crystal (Cry) proteins made by Bacillus thuringiensis are promising...
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