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Joint estimation of contamination, error and demography for nuclear DNA from ancient humans

2015-07-10

Abstract excerpt

When sequencing an ancient DNA sample from a hominin fossil, DNA from present-day humans involved in excavation and extraction will be sequenced along with the endogenous material. This type of contamination is problematic for downstream analyses as it will introduce a bias towards the population of the contaminating individual(s). Quantifying the extent of contamination is a crucial step as it allows researchers...

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Literature Corpus work
c7af119b-e8d4-56cd-8eda-c46834a33d62
DOI
10.1101/022285
Open publication

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Joint estimation of contamination, error and demography for nuclear DNA from ancient humansDOI 10.1101/022285
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