Article

Transcriptome signatures preceding the induction of anti-stalk antibodies elicited by a chimeric hemagglutinin-based universal influenza virus vaccine

2022-05-04

Abstract excerpt

<title>Abstract</title> <p>A phase 1 clinical trial to test the immunogenicity of a chimeric group 1 HA (cHA) universal influenza virus vaccine targeting the conserved stalk domain of the hemagglutinin of influenza viruses was carried out. Vaccination with adjuvanted-inactivated vaccines induced high anti-stalk antibody titers. We sought to identify gene expression signatures that correlate with such induction. M...

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Literature Corpus work: f1ccd286-7177-5fc2-a7c6-9651fea452ec
DOI: 10.21203/rs.3.rs-1547761/v1

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